2026-07-15T17:31:38Z https://icatplus.esrf.fr/oaipmh/request

oai:icatplus.esrf.fr:inv/2391276703 2026-07-02T07:35:43.384Z

4.2 EI 10.15151/ESRF-ES-2391276703 Shibom BASU Shibom Basu 0000-0001-6484-8236 Joana SANTOS Joana Santos 0000-0001-8294-3405 Samuel ROSE Samuel Rose 0000-0003-4824-4066 Ana Rita MIRANDA DE SOUSA PINTO SILVA Ana Rita Miranda De Sousa Pinto Silva 0009-0007-7759-3958 Ana Rita MIRANDA DE SOUSA PINTO SILVA Ana Rita Miranda De Sousa Pinto Silva 0009-0007-7759-3958 Joana SANTOS Joana Santos 0000-0001-8294-3405 Shibom BASU Shibom Basu 0000-0001-6484-8236 Vittoria SCAPIN Vittoria Scapin 0009-0005-9176-507X Example Institute 2029 Data from large facility measurement 2026-06-26T07:30:00Z/2026-06-28T06:00:00Z 2026-06-28T06:00:00Z I CC-BY-4.0 The aim of the JSBG BAG proposal for ID29 beamline is to develop new methods for time-resolved serial crystallography experiments at 4th generation source and to study time dependent structural dynamics of biological macromolecules that are central research topics at the ESRF-EMBL-GR Group. Method developments include the study of radiation damage with µs pulsed X-ray beam at high flux densities and with partially polychromatic X-rays (1% and 0.4%), the implementation and development of various sample delivery methods - mixing in capillary, microfluidics, tape-drive and fixed targets. This further includes development of GPU-based indexing algorithms, data visualization in ICAT, and development of new data collection strategies for pump-probe SSX experiments integrating a nanosecond laser. Biological systems include the study of photoactivable proteins, photoswitchable ligand driven structural dynamics, enzymology, and multi-temp based protein dynamics.