2026-05-31T23:21:58Z https://icatplus.esrf.fr/oaipmh/request

oai:icatplus.esrf.fr:inv/2114569330 2025-06-05T06:00:13.307Z

4.2 EI 10.15151/ESRF-ES-2114569330 Isabel GARCIA-SAEZ Isabel Garcia Saez 0000-0002-4294-710X Kendall CARRASCO Kendall Carrasco 0000-0002-9421-6608 Kendall CARRASCO Kendall Carrasco 0000-0002-9421-6608 David FLOT David Flot 0000-0001-6639-7205 Example Institute 2028 Data from large facility measurement 2025-06-04T07:30:00Z/2025-06-05T06:00:00Z 2025-06-05T06:00:00Z I CC-BY-4.0 The IBS BAG includes teams from IBS (Grenoble) and external groups from CEA-Cadarache (St Paul lez Durance) and IRBA (Brétigny-sur-Orge). We study the structure-function relationships of proteins with a focus on human health, biotechnology and methodology. Most of the projects are a continuation of the MX-2586 proposal and can be grouped under the following themes: host-pathogen interaction, new therapeutic targets, fundamental cellular mechanisms, membrane proteins, biotechnological applications and methodology. Some of these projects use integrative approaches (X-ray crystallography, cryo-EM, SAXS and NMR) together with other biophysical and biochemical studies and, more recently, the use of AI (AlphaFold) to fully understand the complexity of the biological macromolecular systems under study.