2026-06-17T09:39:08Z https://icatplus.esrf.fr/oaipmh/request

oai:icatplus.esrf.fr:inv/2093751548 2025-05-04T06:00:32.682Z

4.2 EI 10.15151/ESRF-ES-2093751548 Tilman GRUNEWALD Tilman Grunewald 0000-0002-5621-605X Tilman GRUNEWALD Tilman Grunewald 0000-0002-5621-605X Moritz STAMMER Moritz Stammer Cajetan MAGER Cajetan Mager Cajetan MAGER Cajetan Mager Moritz STAMMER Moritz Stammer NICOLAS CHARPENTIER Nicolas Charpentier 0000-0002-2664-8935 Henrik BIRKEDAL Henrik Birkedal 0000-0002-4201-2179 Henrik BIRKEDAL Henrik Birkedal 0000-0002-4201-2179 Anastasiia SADETSKAIA Anastasiia Sadetskaia 0000-0003-4344-961X Anastasiia SADETSKAIA Anastasiia Sadetskaia 0000-0003-4344-961X Example Institute 2028 Data from large facility measurement 2025-04-29T06:00:00Z/2025-05-04T06:00:00Z 2025-05-04T06:00:00Z I CC-BY-4.0 Bone is essential for human health and wellbeing due to its central role in the musculoskeletal system. Bone is continually remodeled to maintain bone performance. At the border between old and new bone, cement lines occur. Cement lines are only a few microns across and their composition differs from that of the surrounding bone. However, their structure remains unknown. This information is important for understanding both bone mechanical properties and the signals that govern the behavior of bone cells involved in bone remodeling. Since bone is a 3D composite, the structure must be mapped in 3D. This has recently become possibly by new techniques developed by the proposers. We thus propose to conduct combined SAXS tensor and texture tomography to map the orientation distributions of, respectively, nanostructural features and the bone biomineral nanocrystals. This will enable forming a structural model of cement lines for the first time.