2026-06-22T21:21:07Z https://icatplus.esrf.fr/oaipmh/request

oai:icatplus.esrf.fr:inv/2066300024 2025-03-28T07:00:11.826Z

4.2 EI 10.15151/ESRF-ES-2066300024 Samuel HJORTH JENSEN Samuel Hjorth Jensen Samuel HJORTH JENSEN Samuel Hjorth Jensen Sylvain ENGILBERGE Sylvain Engilberge 0000-0001-8680-6790 LUCAS PETIT Lucas Petit Example Institute 2028 Data from large facility measurement 2025-03-27T07:30:00Z/2025-03-28T07:00:00Z 2025-03-28T07:00:00Z I CC-BY-4.0 We study the structures of a broad diversity of macromolecules from fluorescent to metabolic proteins. One of our primary focus is on solving the 3D structures of enzymes within the MEP pathway, as they represent promising drug targets. Additionally, we are engaged in characterizing new fluorescent proteins derived for instance from bacteriophytochrome. Our research activities also include the development of instrumentation and methodologies, spanning from crystallization to room temperature data collection. We strive to enhance crystal quality for both X-ray and neutron diffraction. Furthermore, we conduct high-throughput screening (HTS) of chemical libraries to identify active ligands targeting proteins with pharmaceutical relevance.