2026-06-01T22:51:21Z https://icatplus.esrf.fr/oaipmh/request

oai:icatplus.esrf.fr:inv/2040659132 2025-04-25T06:00:23.058Z

4.2 EI 10.15151/ESRF-ES-2040659132 Pauline JUYOUX Pauline Juyoux 0000-0003-3153-1376 Maria BACIA Maria Bacia 0009-0007-0036-8373 Ambroise DESFOSSES Ambroise Desfosses Guy SCHOEHN Guy Schoehn 0000-0002-1459-3201 Maria BACIA Maria Bacia 0009-0007-0036-8373 Ambroise DESFOSSES Ambroise Desfosses Example Institute 2028 Data from large facility measurement 2025-04-23T07:00:00Z/2025-04-25T06:00:00Z 2025-04-25T06:00:00Z I CC-BY-4.0 ESRF is privileged to host two state-of-the-art microscopes. Our BAG unites the majority of local labs that utilise cryo-EM to address their diverse structural biology questions, including researchers from the EPN campus (IBS, ESRF, ILL and EMBL) and its vicinity (Cell & Plant Physiology Laboratory LPCV, Grenoble Institut des Neurosciences - GIN, Institute for Advanced Biosciences - IAB). In a nutshell, approximately 30 principal investigators would greatly benefit from Krios time, with 100 different samples proposed. The high demand for EM beamtime is partially met by two Glacios microscopes available on the campus, currently charged with the pre-screening, but also frequently yielding satisfactory structural insights. Nonetheless, the use of a Krios is indispensable for challenging samples (with heterogeneity or limited concentration requiring a large number of images, small proteins, etc.). Only such “difficult cases” will be selected for Krios time at the BAG level.